From Bench to Broken Promise: How Validated Lab Findings Collapse Outside Controlled Conditions
Reproducibility in controlled experiments has dominated headlines, but a quieter and arguably more consequential crisis unfolds when laboratory-validated findings meet the unpredictability of real-world conditions. From pharmaceutical trials to environmental policy, translational failure represents a systemic challenge that demands scholarly attention. This article examines why the journey from laboratory success to practical application so frequently ends in disappointment—and what the research